Controlled Release Excipient

Pharmaceutical formulation of oral dosage forms is continuously challenged by the low solubility of new drug candidates. Pickering emulsions, emulsions stabilized with solid particles, are a promising alternative to surfactants for developing long-term stable emulsions that can be tailored for…
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Pulmonary Drug Delivery Systems: Material and Technological Advances See the new book, edited by Piyush Pradeep Mehta and Vividha Dhapte -Pawar Description: Brings new technologies & material advances together in pulmonary drug delivery systems Emphasis on critical aspects of…
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Pulmonary Drug Delivery Systems: Material and Technological Advances See the new book, edited by Piyush Pradeep Mehta and Vividha Dhapte -Pawar Description: Brings new technologies & material advances together in pulmonary drug delivery systems Emphasis on critical aspects of…
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Mosapride citrate (MC) is a poorly soluble short half-life drug with more pronounced absorption in the stomach. The present study aimed to incorporate MC co-crystals with enhanced solubility into 3D-printed floating tablets. MC co-crystals were prepared via the green method using Saccharin sod. as a…
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Sustained local delivery of meloxicam by polymeric structures is desirable for preventing subacute inflammation and biofilm formation following tissue incision or injury. Our previous study demonstrated that meloxicam release from hot-melt extruded (HME) poly(ε-caprolactone) (PCL) matrices could be…
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Abstract Nanotechnology research over the past several decades has been aimed primarily at improving the physicochemical properties of small molecules to produce druggable candidates as well as for tumor targeting of cytotoxic molecules. The recent focus on genomic medicine and the success of lipid…
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Hot-melt extrusion (HME) has an esteemed place in the pharmaceutical industry with significant applications and advancements spreading over 30 years of development. Currently, the choice of matrix excipients is vast, expanding from all different kinds of synthetic polymers to natural carriers.…
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A 100% MCC sphere, Celphere™ has high sphericity and narrow particle size distribution. Also, Celphere™ is less damaged during film coating process because of its high mechanical strength. With regard to comparison with sugar spheres, Celphere™ can prevent agglomeration during film coating process…
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Introduction With target-oriented drug discovery and an increasing focus on specialized medicines, the manufacturing of final drug products is becoming more and more complex. The processing and formulation of active pharmaceutical ingredients (APIs) designed with a specific target and functionality…
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Introduction Poly (lactic-co-glycolic acid) or PLGA, a highly hydrophobic copolymer comprised of lactic acid and glycolic acid, has been approved in many drug products and medical devices.1 Over the years since the first approved in 1997, PLGA has been widely studied polymer in the industry because…
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