DC excipient

The study reported here aimed to develop and optimize the S-SNEDDS tablet of bosentan (BOS) and to investigate its pharmacokinetic and biodistribution properties. The BOS-loaded SNEDDS have been developed and characterized in a previous study. The BOS-loaded SNEDDS formulation was converted to…
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Pharma Solutions at IFF provides you access to one of the broadest microcrystalline cellulose (MCC) portfolios in the industry. Backed by decades of innovation, and expertise, Avicel® PH offers a long history of manufacturing the highest-quality pharmaceutical grade MCC. Our deep polymer…
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With the emergence of quality by design (QbD), it becomes imperative to gain understanding of the impact of batch-to-batch variability of raw materials on the performance of processes. Feeding is the first unit of operation in a continuous manufacturing line and is critical for the final product…
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Abstract We designed a bioequivalent tablet form of solifenacin succinate (SOL) with an improved storage stability using a direct compression (DC) technique. An optimal direct compressed tablet (DCT) containing an active substance (10 mg), lactose monohydrate, and silicified microcrystalline…
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Press Release Wilmington, Del., June 20, 2023 - Ashland is introducing Polyplasdone™ Plus, a co-processed multifunctional direct compression superdisintegrant containing a glidant and lubricant. Saving time and simplifying development, the multifunctional disintegrant offers superior powder flow…
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Taste masking is critical to improving the compliance of pediatric oral dosage forms. However, it is challenging for extremely bitter lisdexamfetamine dimesylate (LDX) with a long half-life and given in large dose. The present study aims to develop an immediate-release, taste-masked lisdexamfetamine…
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Pharma Excipients & Roquette present the new webinar: Solving capping challenges using mannitol as an excipient model Date & Time: Jun 27, 2023 03:00 PM CET, 9:00 AM EST Register here Description: During drug development formulators are focusing on Improving patient…
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抽象的制药行业is undergoing a paradigm shift towards continuous processing from batch, where continuous direct compression (CDC) is considered to offer the most straightforward implementation amongst powder processes due to the relatively low number of unit operations or…
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Solid dosage forms based on hypromellose (HPMC) with prolonged/extended drug release are very important from the research and industrial viewpoint. In the present research, the influence of selected excipients on carvedilol release performance from HPMC-based matrix tablets was studied. A…
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1. Introduction The introduction of continuous manufacturing of tablets has been gaining momentum, because it offers reductions in development and manufacturing costs and time and improved reliability of quality assurance. In this study, grades of Ceolus™, microcrystalline cellulose (MCC) in…
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