Flavour / Flavor

Kollicoat® Smartseal 30 D and Kollicoat® Smartseal 100 P can help formulators tackle challenges when handling bitter active ingredients. It offers superior protection from unpleasant drug taste for minitablets, pellets, particles, and granules used in orally disintegrating dosage forms, improving…
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Abstract Over the past few years, 3D printing technologies have gained interest in the development of medicinal products for personalized use at the point of care. The printing of drug products offers personalization and flexibility in dose, shape/design, and flavor, potentially enhancing…
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Abstract Objectives This review aims at gleaning the currently available research reports that relate to 3D printlets for paediatric patients, and especially the excipients used to produce various colours, flavours, shapes and sizes. Methods A thorough literature review on paediatric 3D printed…
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This study demonstrated the implementation of a liquisolid technique to formulate directly compressible orally disintegrating tablets (ODTs). Cannabidiol (CBD), a hydrophobic cannabinoid, was prepared as a liquisolid powder using microcrystalline cellulose–colloidal silicon dioxide as a…
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According to the Quality by Design (QbD) concept, Design of Experiment (DoE) was used to indicate critical process parameters and optimize the fluid bed coating of minitablets in a laboratory size batch. Full factorial design was employed to increase knowledge of the process for three kinds of…
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Colonic targeting of orally applied therapeutic drugs remains a challenge. Tablet coatings relying on gastrointestinal pH and colonic bacterial enzymes as triggers in association with an inner alkaline layer are expected to improve targeting efficiency. Mesalazine release from three differently…
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Over the past few decades, researchers and companies have been trying to develop novel drug delivery systems to ensure safety, efficacy, compliance, and patient acceptability. Nowadays drug discovery and development are expensive, complex, and time-consuming processes, but trends are moving toward…
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Obtention定制的剂型之一main attractions of 3D printing in pharmaceuticals. In this sense, children are one of the groups within the population with a greater need for drug doses adapted to their requirements (age, weight, pathological state…), but most 3D printed oral…
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Sanhuang tablets (SHT) had a broad antibiotic spectrum with high efficiency and low toxicity. However, the clinical application was seriously limited by extremely bitter taste. A novel powder coating technology was established to mask the bitter taste of Sanhuang powder (SHP). Initially, the type…
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The major part (approx. 80%) of new drug actives are poorly soluble. Several techniques are used to enhance solubility including but lot limited to alternative salt forms, particle size reduction and solubility-enhancing excipients. Similar to APIs, many excipients are bitter or have other…
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