甜味剂

ABSTRACT Introduction Increasing attention is being afforded to understanding the bidirectional relationships that exist between oral medications and the gut microbiota, in an attempt to optimize pharmacokinetic performance and mitigate unwanted side effects. While a wealth of research has…
Read More...

Abstract Objectives This review aims at gleaning the currently available research reports that relate to 3D printlets for paediatric patients, and especially the excipients used to produce various colours, flavours, shapes and sizes. Methods A thorough literature review on paediatric 3D printed…
Read More...

Orodispersible drug formulations are a current trend in the pharmaceutical industry, mostly intended for pediatric and geriatric patients. Oral lyophilizates are solid forms, intended either to be placed in the mouth or to be dispersed (or dissolved) in water before administration. The correct…
Read More...

Speed. Precision. Patient-centricity. Roquette´s PEARLITOL® 200 GT granulated mannitol is here to revolutionize direct compression. Realize the potential of novel drug formats with smaller, harder tablets produced at unprecedented speeds – without compromising on quality. PEARLITOL® 200 GT…
Read More...

The absence of oral liquid pharmaceutical forms appropriate for use in pediatric and adult patients with difficulty swallowing is a public health problem, especially in the hospital context. Baclofen is a muscle relaxant of choice for treating spasticity, generally marketed only in tablet form,…
Read More...

Understanding of the sweetness of an organic or inorganic substance is complex process and it is ingrained with the intricacies of psychological perception, molecular structure, chemical nature and environmental conditions e.g. pH, temperature, type of medium etc. Sucrose tastes sweet but when it is…
Read More...

Praziquantel (PZQ) is an antihelmintic drug used worldwide against Schistosomiasis, despite its low solubility, bioavailability and the disgusting taste. This research represents a preliminary screening of 6 selected sweeteners in terms of their aptitude to be ground with PZQ, towards the…
Read More...

galenIQ™ is a sweet-tasting water soluble filler binder derived from sugar beet. It is available in several different morphological forms which are suitable for the formulation and manufacture of oral solid dosage forms including tablets, effervescents, medicated lozenges and powder blends for…
Read More...

Improving patient experience and compliance Better drug design and delivery options can help improve the likelihood that patients will be more willing to take their medications as prescribed. Suspensions are defined as finely divided undissolved drugs dispersed in liquid vehicles. They can be a…
Read More...

Obtaining orodispersible tablets (ODT) containing substances from the 2nd Biopharmaceutical Class has raised concerns as the dissolution test is challenging. This study aimed to select suitable excipients for developing orodispersible tablets containing cannabidiol (CBD) by direct compression…
Read More...